Melanosis lacks a substantial melanocytic proliferation, nesting pattern of melanocytes, or melanocyte atypia. Dendritic melanocytes are normal in number or only slightly increased along the basal layer of the epidermis in association with hyperpigmentation (Fig. 6). On occasion, the melanin pigment is also located in the upper dermis. Sep 02, 2009 · Causes & Home Remedies for Vaginal Skin Discoloration And Pigmentation. Moreover, it is absolutely normal for the color of the labia and the skin around the vagina to be darker as compared to the rest of your body. The color of your skin in the vaginal area may range from pink to purple to dark brown, depending upon factors such as your ethnicity, age, body weight, complexion, and so on.
Vaginal melanoma is a rare malignancy that originates from melanocytes in the vaginal epithelium. It is also known as a melanocytic tumor or as a malignant melanoma. It is aggressive and infrequently cured. The five year survival rate is approximately 21%. It was first described in 1887 and only 500 cases are found in current literature.Specialty: Oncology/gynecology. Jul 22, 2013 · Vaginal primary malignant melanoma is a rare and very aggressive tumor. It most commonly occurs in postmenopausal women, with a mean age of 57 years. Our patient is an 80-year-old, postmenopausal Greek woman presented with a complaint of abnormal vaginal bleeding.Cited by: 8.
Aug 12, 2019 · This, too, is normal. Your vagina might become darker when you are having sex or sexually aroused, thanks to the copious blood flow that goes to that area when you are ready to have sex. The vaginal tissue swells and becomes lubricated, and the color of the clitoris and inner lips gets darker. The melanin-concentrating hormone (MCH) receptors form a small family of two receptor subtypes MCH 1 and MCH 2. They exist throughout species, from fishes to mammals. They exist throughout species, from fishes to mammals.