Epirubicin hydrochloride is approved to be used with other drugs to treat: Breast cancer. It is used after surgery in patients whose cancer has spread to the lymph nodes under the arm. Epirubicin hydrochloride is also being studied in the treatment of other types of cancer. More About Epirubicin Hydrochloride. Epirubicin is a 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin.Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis.
Apr 30, 2018 · Epirubicin (Pharmorubicin®) is a chemotherapy drug that may be used to treat different cancers. It is best to read this information with our general information about chemotherapy and the type of cancer you have. Your doctor will talk to you about this treatment and its possible side effects. It is used to treat breast cancer. It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take Epirubicin? If you have an allergy to epirubicin or any other part of epirubicin. If you are allergic to any drugs like this one, any other drugs, foods, or other substances.Drug class: antibiotics/antineoplastics.
Thirty-six consecutive patients with breast cancer and liver metastases with abnormal liver biochemistry were treated with epirubicin 25 mg m-2 i.v. weekly. No dose modification was made for abnormal liver biochemistry, but dose intensity was adjusted by delaying treatment according to Cited by: 29. Nov 09, 2018 · Epirubicin is a cancer medication that interferes with the growth and spread of cancer cells in the body. Epirubicin is used to treat breast cancer.
Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is marketed by Pfizer under the trade name Ellence in the US and Pharmorubicin or Epirubicin Ebewe elsewhere.Metabolism: Hepatic glucuronidation and oxidation. The dosage of epirubicin hydrochloride is defined by the oncology medical team, depending on the patient’s height and weight, general health or other health problems, as well as the type of breast cancer and additional treatments recommended. Epirubicin Hydrochloride (Ellence) for Breast Cancer.